2016 Pitt Panthers, 8-5 (5-3 ACC)
| 2016 |
9/3 |
Villanova |
Heinz Field |
W, 28-7 |
| 2016 |
9/10 |
Penn State |
Heinz Field |
W, 42-39 |
| 2016 |
9/17 |
Oklahoma State |
Stillwater, OK |
L, 38-45 |
| 2016 |
9/24 |
North Carolina |
Chapel Hill, NC |
L, 36-37 |
| 2016 |
10/1 |
Marshall |
Heinz Field |
W, 43-27 |
| 2016 |
10/8 |
Georgia Tech |
Heinz Field |
W, 37-34 |
| 2016 |
10/15 |
Virginia |
Charlottesville, VA |
W, 45-31 |
| 2016 |
10/27 |
Virginia Tech |
Heinz Field |
L, 36-39 |
| 2016 |
11/5 |
Miami (Fla.) |
Miami, FL |
L, 28-51 |
| 2016 |
11/12 |
Clemson |
Clemson, SC |
W, 43-42 |
| 2016 |
11/19 |
Duke |
Heinz Field |
W, 56-14 |
| 2016 |
11/26 |
Syracuse |
Heinz Field |
W, 76-61 |
| 2016 |
12/28 |
Northwestern (Pinstripe Bowl) |
New York, NY |
L, 24-31 |
